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PanoBrain

PanoBrain / Fully Automatic Brain Slice Analyzer

Simplify Neuroscience Workflows

PanoBrain rapidly scans brain slices to capture high-resolution digital panoramic images, then automatically performs quantitative analysis such as brain-region segmentation, atlas registration, and cell counting. It automates the full workflow from imaging to data processing and reshapes neuroscience research workflows

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One-click Atlas Registration

One-click Atlas Registration

One-click registration

Automatically identifies brain slices and matches them to the Allen Brain Atlas

Cell Recognition and Counting

Cell Recognition and Counting

Automated quantification

Reduces manual intervention while ensuring data consistency and accuracy, facilitating the extraction of reliable experimental results

Intelligent Scan Path Planning

Intelligent Scan Path Planning

One image per minute

Automatically identifies ROIs and plans scan paths. A brain slice scan takes less than 1 minute; with a 10X objective and DAPI & GFP dual channels, a single brain slice takes only 40 seconds

High-precision Autofocus

High-precision Autofocus

Thick-slice surface imaging

Precisely focuses on the surface of thick brain slices... and keeps focal planes consistent across all channels, generating high-quality multi-channel data

One-click Brain Atlas Registration

Align with standard atlases for efficient exploration of the brain

Rat Brain Atlas

Rat Brain Atlas

Mouse Brain Atlas

Mouse Brain Atlas

Macaque Brain Atlas

Macaque Brain Atlas

Ferret Brain Atlas

Ferret Brain Atlas

One-click automatic atlas registration, free from tedious work

One-click automatic atlas registration, free from tedious work

Comprehensive slice registration for a hassle-free workflow

Tilted Brain Slice

Tilted Brain Slice

Damaged Brain Slice

Damaged Brain Slice

Half Brain Slice

Half Brain Slice

Precise positioning with reliable manual adjustments

Side-by-side Standard 2D Atlas

Side-by-side Standard 2D Atlas

Bregma Positioning

Bregma Positioning

Automated Fluorescence Quantitative Analysis

Automatic Recognition and Statistics

Automatic Recognition and Statistics

Supports automatic recognition of DAPI, c-Fos, neurons, glial cells, and other signals, with statistics for positive signal count, area, and fluorescence intensity

Personalized Statistical Region Selection

Personalized Statistical Region Selection

Supports whole-brain, left-right brain, and custom brain-region statistics to meet diverse counting needs

Hierarchical Counting Statistics

Hierarchical Counting Statistics

Exports results to Excel in a hierarchical format, clearly linking parent and child brain-region data, making complex anatomical statistics easy to interpret

High-performance Slice Scanner

One Image per Minute

One Image per Minute

Automatically identifies ROIs and plans scan paths, keeping each brain slice scan under 1 minute

99% Uniformity

99% Uniformity

Uniform illumination coupled with global background correction achieves up to 99% field uniformity, effortlessly yielding high-quality multi-channel fluorescence images

No Channel Crosstalk

No Channel Crosstalk

Universal fluorescence channel configurations cover common fluorescence imaging applications, with customizable narrow-band excitation and emission filters to eliminate crosstalk anxiety

Low Phototoxicity

Low Phototoxicity

Strobe illumination provides millisecond-level high instantaneous power only during camera exposure, reducing phototoxic effects caused by continuous illumination

Simplification Beyond Expectations

Side LED Illumination

Side-mounted scattered LED illumination enables high-contrast visualization of fluorescent samples, eliminating the need for manual marker-pen positioning

Progress Indicator Light

An embedded ring light shows scan status and progress through color and completion state, making experiment progress easy to track

Parameter Templates

Scan parameters, image contrast, analysis regions, and export size settings can be saved as templates for fast reuse

Batch Export

Supports batch export of multi-channel fluorescence images as single-channel pseudo-color or grayscale, and multi-channel overlays. It seamlessly combines flexible image type selection with highly efficient batch processing

Bring PanoBrain Into Your Lab

Move brain slice scanning, atlas registration, and quantitative analysis into a more efficient automated workflow

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PanoBrain | Meca Scientific